ANUSOL™ Multi-Symptom Ointment Your patient should apply the ointment freely to the affected area every 4 hours, or as needed, and after each bowel movement. ANUSOL™ Multi-Symptom Suppositories Your patient should remove a suppository from the foil wrapper and insert it into the rectum. They should use one suppository in the morning, one at bedtime, and one after each bowel movement.