ANUSOL-HC™ OINTMENT Patients should apply ANUSOL-HC™ OINTMENT (Hydrocortisone Acetate and Zinc Sulfate Monohydrate) internally and on the exterior surface of the anus in the morning, at bedtime, and after each bowel movement, or as directed by a physician. ANUSOL-HC™ SUPPOSITORIES Patients should remove wrapper from the ANUSOL-HC™ SUPPOSITORIES and insert suppository into the rectum in the morning, at bedtime, and after each bowel movement, or as directed by a physician.